Correlation of Salivary Retinol Binding Protein 4 (RBP4) Levels and Periodontal Severity in Patients with Chronic Periodontitis

Pro-inflammatory cytokines play a vital role in periodontitis, obesity and chronic diseases. Retinol binding protein 4 (RBP4), novel adipokine has been implicated as pro-inflammatory marker other systemic In periodontal disease, RBP4 correlated with markers of low-grade inflammation. can directly induce the production mediators involved leukocyte recruitment adherence, including vascular cell adhesion molecule-1, intercellular molecule-1 etc. The present study explores correlation salivary levels parameters, BMI, WHR periodontitis patients. A total 91 subjects were included. Full mouth probing depth, clinical attachment levels, bleeding on probing, BMI & recorded. Unstimulated samples collected analyzed for levels. Pearson’s coefficient test was done to correlate Periodontal parameters. Correlation between RBP negative, weak not significant (r = - 0.016, p 0.880; r 0.165, 0.120). PPD, CAL statistically 0.076, 0.475; 0.106, 0.318). underweight Group, values did any normal weight group, only (p 0.47). overweight morbidly obese no found There is association RBP4, Chronic